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| Title: | ULTRAHIGH MAGNETIC MOMENTS OF CORE-SHELL NANOCLUSTERS FOR BIOMEDICAL APPLICATIONS
This work is supported by NSF Idaho-EPSCoR, ONR and DOE/PNNL. |
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| DOI No: | 10.1142/9789812701879_0049 | |
| Source: | CLUSTERS AND NANO-ASSEMBLIES (pp 423-428) | |
| Author(s): | YOU QIANG
Contact information: Tel: 208-885-7558. Department of Physics, University of Idaho, Moscow, ID 83844-0903, USA JIJI ANTONY Department of Physics, University of Idaho, Moscow, ID 83844-0903, USA CHANDRA S. KAKARAPARTHI Department of Physics, University of Idaho, Moscow, ID 83844-0903, USA SWETA PENDYALA Department of Physics, University of Idaho, Moscow, ID 83844-0903, USA |
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| Abstract: | Magnetic nanoparticles with suitable biocompatible coatings are becoming increasingly important for several biomedical applications in tagging, imaging, sensing and separation in recent years. Most magnetic particles or beads used in biomedical applications are based on ferromagnetic iron oxides with very low magnetic moment (between 20 and 80 emu/g). Here we report a new approach to synthesize monodispersive core-shell nanostructured clusters with ultrahigh specific magnetic moments above 250 emu/g. The Fe nanoclusters with size range from 2 nm to 100 nm are produced from a newly developed cluster source and go to a deposition chamber, where a chemical reaction starts and the nanoclusters are coated with Fe oxides before depositing on surface. HRTEM images show the coatings are very uniform. The core-shell nanoclusters are superparamagnetic at room temperature for the size less then 15 nm. These nanoclusters with ultrahigh moments can enhance dramatically the contrast for MRI, or reduce the concentration of magnetic particle needs for cell separation, or make drug delivery possible with much lower magnetic field gradients. | |
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