| Home | Organizers | Proceedings Editors | Proceedings Contributors | Search | | ||
|
|
|||
|
||||
|
|
||||
| Title: | INVESTIGATION OF ELECTRICAL DEFIBRILLATION OF CHAOTICALLY FIBRILLATING HUMAN VENTRICULAR MYOCARDIUM IN A COMPUTER MODEL | |
| DOI No: | 10.1142/9789812702234_0043 | |
| Source: | ADVANCES IN ELECTROCARDIOLOGY 2004 (pp 148-151) | |
| Author(s): | I. M. POPP
Insitute of Biomedical Engineering, University Karlsruhe (TH), Kaiserstr. 12, 76128, Karlsruhe, Germany G. SEEMANN Insitute of Biomedical Engineering, University Karlsruhe (TH), Kaiserstr. 12, 76128, Karlsruhe, Germany O. DÖSSEL Insitute of Biomedical Engineering, University Karlsruhe (TH), Kaiserstr. 12, 76128, Karlsruhe, Germany |
|
| Abstract: | Defibrillation is the most important measure of resuscitation aiming at restoration of the physiological heart rhythm. A complete understanding of the defibrillation mechanism has not been achieved yet. The research presented in this article gives a mathematical computer simulation of the defibrillation of chaotically fibrillating human ventricular myocardium. The study was done with a model representing a three-dimensional wedge of human ventricular myocardial tissue. The cellular electrophysiology was described with the Priebe-Beuckelmann model. The electrical activity of the cardiac tissue was calculated with a bidomain model. A spiral wave was induced in the myocardium with standard S1-S2 protocols. The myocardium was brought into a chaotically fibrillating state by breaking the spiral wave. Few hundred milliseconds after the chaotically fibrillation started, monophasic electrical defibrillating shocks were applied through planar electrodes. The defibrillation shocks were applied at different moments. At each chosen moment we studied both cases of electrical polarity. The reaction of myocardium was studied during the following 400 ms. The results are indicating important information related to the factors, which are influencing the defibrillation success. | |
| Full Text: | View full text in PDF format (257KB) | |
| TOC: | Back to Table of Contents | |
|
||