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Title:INVESTIGATION OF THE MAGNETIC PARTICLE IMAGING SIGNAL'S DEPENDENCY ON FERROFLUID CONCENTRATION
DOI No:10.1142/9789814324687_0010
Source:MAGNETIC NANOPARTICLES
Particle Science, Imaging Technology, and Clinical Applications
(pp 73-78)
Author(s):J.-P. GEHRCKE
Department of Experimental Physics 5, University of Würzburg, Am Hubland, D - 97074 Würzburg, Germany

M. A. RÜCKERT
Department of Experimental Physics 5, University of Würzburg, Am Hubland, D - 97074 Würzburg, Germany

University of Applied Sciences Würzburg-Schweinfurt, Ignaz-Schön-Straße 11, D - 97421 Schweinfurt, Germany

T. KAMPF
Department of Experimental Physics 5, University of Würzburg, Am Hubland, D - 97074 Würzburg, Germany

W. H. KULLMANN
University of Applied Sciences Würzburg-Schweinfurt, Ignaz-Schön-Straße 11, D - 97421 Schweinfurt, Germany

P. M. JAKOB
Department of Experimental Physics 5, University of Würzburg, Am Hubland, D - 97074 Würzburg, Germany

Research Center Magnetic Resonance Bavaria (MRB) e.V., Am Hubland, D - 97074 Würzburg, Germany

V. C. BEHR
Department of Experimental Physics 5, University of Würzburg, Am Hubland, D - 97074 Würzburg, Germany

Abstract:Evaluation of the Magnetic Particle Imaging (MPI) signal in terms of LANGEVIN's single particle model of paramagnetism (SPM) is well-established. The SPM does not consider interparticle interactions and therefore is only valid for very low ferrofluid concentrations c, yielding a linear relation between single harmonics' amplitudes A and c. Motivated by MPI applications that potentially bear local particle densities significantly exceeding the SPM's scope of validity, the impact of increasing ferrofluid concentration on the MPI signal was investigated experimentally. The results exhibit a significant nonlinear relation between c and A and therefore show a strong deviation from the SPM, even for relatively small concentrations. Considering this fact can be crucial for image reconstruction in MPI.
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